Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g19447.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g19447.t1
Gene ID Description PCC Relationship
g19447.t1TARGETING PROTEIN FOR XKLP21positive
g1454.t1DRAB5-RELATED0.98positive
g3735.t1--0.98positive
g17234.t1KINESIN-LIKE PROTEIN KLP-30.97positive
g11429.t1UNCHARACTERIZED0.97positive
g95.t1U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B0.97positive
g34764.t1MACROPHAGE ERYTHROBLAST ATTACHER-RELATED0.97positive
g23612.t1CHEMOKINE C-C MOTIF RECEPTOR 10.97positive
g4727.t1HISTONE H30.97positive
g18087.t1HISTONE H2A0.96positive
g16081.t1T-BOX PROTEIN-RELATED0.96positive
g29808.t1SCHLAFEN0.96positive
g34963.t1MYC PROTO-ONCOGENE0.96positive
g49.t1RED PROTEIN IK FACTOR CYTOKINE IK0.96positive
g6553.t1SCAFFOLD ATTACHMENT FACTOR B-RELATED0.96positive
g5654.t1CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B0.96positive
g15745.t1PROTEIN IWS1 HOMOLOG0.96positive
g21423.t1--0.95positive
g7396.t1CYTOCHROME B50.95positive
g23651.t1SPLICING FACTOR 3B SUBUNIT 40.95positive
g31971.t1UNCHARACTERIZED0.95positive
g21523.t1ZINC FINGER PROTEIN ZIC AND GLI0.95positive
g14630.t1--0.95positive
g10489.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT0.94positive
g14440.t1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN0.94positive
g3112.t1TRIHELIX TRANSCRIPTION FACTOR ASIL20.94positive
g27178.t1RNA-BINDING PROTEIN RELATED0.94positive
g5293.t1AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN0.94positive
g27841.t1HIGH MOBILITY GROUP PROTEIN DSP10.94positive
g31105.t1PUTATIVE-RELATED0.94positive
g23741.t1--0.94positive
g18089.t1HISTONE H30.94positive
g27038.t1MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB10.93positive
g989.t1FI02826P0.93positive
g22179.t1IQ DOMAIN-CONTAINING PROTEIN D0.93positive
g8877.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.93positive
g8693.t1CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR0.93positive
g20511.t1RAS-RELATED PROTEIN RAB0.93positive
g14078.t1SODIUM/POTASSIUM/CALCIUM EXCHANGER0.93positive
g5545.t1CXYORF10.92positive
g25807.t1NEUROTRANSMITTER GATED ION CHANNEL0.92positive
g11038.t1HELIX LOOP HELIX PROTEIN 21-RELATED0.91positive
g13224.t1UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER0.91positive
g16629.t1ADP-DEPENDENT GLUCOKINASE0.90positive
g11558.t1DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 303 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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