Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g19647.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g19647.t1
Gene ID Description PCC Relationship
g19647.t1ACYL-COA-BINDING PROTEIN, ACBP1positive
g5463.t1S-FORMYLGLUTATHIONE HYDROLASE0.98positive
g15831.t1PEROXIREDOXIN0.98positive
g8878.t1EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 100.96positive
g11346.t1ALDO/KETO REDUCTASE0.96positive
g14773.t1RTDR10.96positive
g15083.t1NUCLEOSIDE DIPHOSPHATE KINASE0.96positive
g14945.t1CALBINDIN0.95positive
g23006.t1ARP2/3 COMPLEX 34 KDA SUBUNIT0.95positive
g27172.t1--0.95positive
g516.t1NEPHROCYSTIN0.95positive
g15394.t1PROTEIN CBG204880.95positive
g3940.t1UNCHARACTERIZED0.94positive
g4078.t1O-METHYLTRANSFERASE-RELATED0.94positive
g27173.t1NYD-SP28 PROTEIN0.94positive
g18366.t1ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE0.94positive
g6172.t1DYNEIN REGULATORY COMPLEX SUBUNIT 70.94positive
g4960.t1PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN0.94positive
g28697.t1A-KINASE ANCHOR PROTEIN 140.94positive
g34967.t1GTP-BINDING PROTEIN-RELATED0.93positive
g11027.t1ENOLASE0.93positive
g6915.t1UNCHARACTERIZED0.93positive
g27128.t1PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR0.93positive
g26208.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 890.92positive
g30396.t1MSF1/PX19 RELATED0.92positive
g27003.t1RAGULATOR COMPLEX PROTEIN LAMTOR40.92positive
g10319.t1UNCHARACTERIZED0.92positive
g16449.t1--0.92positive
g34702.t1FERRITIN0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 122 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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