Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g19976.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g19976.t1
Gene ID Description PCC Relationship
g19976.t1PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 11positive
g3851.t1SI:DKEY-256H2.10.97positive
g30469.t1SH3 MULTIPLE DOMAIN0.97positive
g7920.t1ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED0.96positive
g9879.t1MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED0.96positive
g8000.t1E3 UBIQUITIN-PROTEIN LIGASE HECTD30.96positive
g35990.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 140.96positive
g5569.t1PROTEIN KINASE C, MU0.95positive
g6204.t1OLIGOPHRENIN 10.95positive
g12279.t1WD40 REPEAT PROTEIN 12, 370.95positive
g19648.t1CENTROMERE PROTEIN E0.95positive
g7802.t1ATP-DEPENDENT DNA HELICASE0.95positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.95positive
g10216.t1--0.94positive
g13588.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR0.94positive
g22154.t1N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D10.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 62 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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