Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g2000.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g2000.t1
Gene ID Description PCC Relationship
g2000.t1--1positive
g7431.t1--0.97positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.97positive
g28027.t1FI24210P10.97positive
g2191.t1RUBY-EYE2-LIKE PROTEIN0.96positive
g29384.t1--0.96positive
g15081.t1-0.96positive
g27755.t1HOMER0.96positive
g9525.t1-0.96positive
g27861.t1CENTROSOMAL PROTEIN OF 170 KDA0.96positive
g7543.t1--0.96positive
g4160.t1--0.96positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.96positive
g295.t1--0.96positive
g12341.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.95positive
g633.t1MOLTING PROTEIN MLT-40.95positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.95positive
g27269.t1ZINC FINGER PROTEIN0.95positive
g3586.t1NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 10.95positive
g23138.t1UBIQUITIN SPECIFIC PROTEINASE0.95positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.95positive
g12233.t1--0.95positive
g8358.t1GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED0.95positive
g11254.t1SPINSTER0.95positive
g6432.t1SWAP-70 RECOMBINASE0.95positive
g5326.t1D-GLUCURONYL C5-EPIMERASE0.95positive
g22088.t1WD40 REPEAT PROTEIN0.95positive
g6210.t1METHYLMALONYL-COA MUTASE0.94positive
g19595.t1IP01015P-RELATED0.94positive
g8686.t1AGAP003710-PA0.94positive
g23744.t1LD33804P0.94positive
g4562.t1NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE0.94positive
g1834.t1TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED0.93positive
g27885.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED0.93positive
g2972.t1PARTITIONING DEFECTIVE 3 RELATED0.93positive
g7500.t1PROTEIN CBG162000.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 245 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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