Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g20306.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g20306.t1
Gene ID Description PCC Relationship
g20306.t1UNCHARACTERIZED1positive
g6832.t1ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL0.98positive
g35262.t1NADP-SPECIFIC ISOCITRATE DEHYDROGENASE0.98positive
g16307.t1GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT0.98positive
g17650.t1STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX10.97positive
g6335.t1ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER0.97positive
g6629.t1KINESIN-ASSOCIATED PROTEINS0.97positive
g27840.t1POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE0.97positive
g4844.t1--0.97positive
g2959.t1E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED0.97positive
g1630.t1DIPHTHAMIDE BIOSYNTHESIS PROTEIN0.97positive
g17122.t1NUCLEOLAR PROTEIN 80.96positive
g12274.t1ATP-CITRATE SYNTHASE0.96positive
g25456.t1SERYL-TRNA SYNTHETASE0.96positive
g11356.t1MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN0.96positive
g14667.t1PROTEIN SIDEKICK0.96positive
g26470.t1NUCLEAR EXPORT MEDIATOR FACTOR NEMF0.96positive
g363.t1MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED0.96positive
g35064.t1PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN0.96positive
g14901.t1TRANSLATION INITIATION FACTOR EIF-2B0.96positive
g8379.t1V-TYPE PROTON ATPASE SUBUNIT B0.96positive
g27209.t1ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD0.96positive
g5627.t1ALPHA-PROTEIN KINASE VWKA0.96positive
g3077.t1EXPRESSED PROTEIN0.96positive
g12582.t1NUCLEOREDOXIN0.95positive
g12782.t1FLAVIN REDUCTASE-RELATED0.95positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 104 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP