Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g20801.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g20801.t1
Gene ID Description PCC Relationship
g20801.t1WD REPEAT-CONTAINING PROTEIN 551positive
g27949.t1MYOTONIC DYSTROPHY S/T KINASE-RELATED0.94positive
g19028.t1WD REPEAT AND HMG-BOX DNA BINDING PROTEIN0.92positive
g5379.t1FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN0.89positive
g31982.t1PESCADILLO - RELATED0.89positive
g10422.t1DNA HELICASE RECQ FAMILY MEMBER0.89positive
g19552.t1SEC31-RELATED PROTEIN0.88positive
g24048.t1PROTEASOME MATURATION PROTEIN UMP10.86positive
g4204.t1WD40 REPEAT PROTEIN0.85positive
g31561.t1BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED0.85positive
g1544.t126S PROTEASOME REGULATORY SUBUNIT0.84positive
g30915.t126S PROTEASOME REGULATORY SUBUNIT0.84positive
g1466.t1COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR770.83positive
g30302.t1TOLL-INTERACTING PROTEIN0.83positive
g11946.t1TETRATRICOPEPTIDE REPEAT PROTEIN 310.83positive
g14202.t1KIAA0586 PROTEIN0.83positive
g5657.t1RING FINGER PROTEIN 170.83positive
g1691.t1DUF4605 DOMAIN-CONTAINING PROTEIN0.82positive
g8748.t1MEMBRALIN/KINETOCHORE PROTEIN NUF20.82positive
g5565.t1DYNACTIN 1-RELATED MICROTUBULE-BINDING0.81positive
g3217.t1GPALPP MOTIFS-CONTAINING PROTEIN 10.81positive
g17854.t150S RIBOSOMAL PROTEIN L210.80positive
g13063.t1SODIUM/CHLORIDE DEPENDENT TRANSPORTER0.80positive
g11944.t1CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN0.80positive
g34987.t1STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 50.79positive
g2198.t1APOPTOSIS-INDUCING FACTOR 10.78positive
g7881.t1RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP10.77positive
g34217.t1DUF3504 DOMAIN-CONTAINING PROTEIN0.74positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 174 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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