Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g22068.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g22068.t1
Gene ID Description PCC Relationship
g22068.t1BONUS, ISOFORM C-RELATED1positive
g22788.t1SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC0.99positive
g16919.t1ES-2 PROTEIN - RELATED0.99positive
g16482.t1S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED0.98positive
g21084.t1TRANSLATION FACTOR GUF1-RELATED0.98positive
g11633.t1TRANSCRIPTIONAL ADAPTER 10.98positive
g18671.t1BATTENIN0.98positive
g2568.t1--0.98positive
g11776.t1PR DOMAIN ZINC FINGER PROTEIN0.98positive
g32018.t1--0.97positive
g9738.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.97positive
g295.t1--0.97positive
g3095.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.97positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.97positive
g35539.t1EXPORTIN-60.97positive
g4804.t1FACTOR VIII-ASSOCIATED GENE 10.97positive
g402.t1--0.97positive
g1835.t1ANOCTAMIN0.97positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.97positive
g27242.t1UNCHARACTERIZED0.97positive
g10333.t1HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.97positive
g1978.t1ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER0.97positive
g20275.t1TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 30.97positive
g30205.t1RAB GDP/GTP EXCHANGE FACTOR0.96positive
g17718.t1--0.96positive
g17796.t1PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED0.96positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.96positive
g16665.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.96positive
g1243.t1TOLL-LIKE RECEPTOR0.96positive
g11711.t1BATTENIN0.96positive
g12755.t1--0.96positive
g6584.t1GATA-TYPE ZINC FINGER PROTEIN 10.96positive
g4160.t1--0.96positive
g13539.t1OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL0.96positive
g4334.t1--0.96positive
g12576.t1PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 10.96positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.96positive
g5767.t1UNCHARACTERIZED0.96positive
g15757.t1UNCHARACTERIZED0.96positive
g27040.t1TRNA METHYLTRANSFERASE0.95positive
g3958.t1UNCHARACTERIZED0.95positive
g2867.t1GLYCOPROTEIN HORMONE RECEPTOR0.95positive
g4552.t1F-BOX/WD REPEAT-CONTAINING PROTEIN 20.95positive
g23270.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I0.95positive
g314.t1WD REPEAT-CONTAINING PROTEIN 270.95positive
g24390.t1PROTECTION OF TELOMERES 10.95positive
g17146.t1SORTING NEXIN-29-RELATED0.95positive
g28274.t1--0.95positive
g353.t1ZINC FINGER PROTEIN ZIC AND GLI0.94positive
g23736.t1--0.94positive
g16138.t1UNCHARACTERIZED0.94positive
g34901.t1ACYL-COA DESATURASE0.94positive
g7497.t1CULTURE SPECIFIC PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00130)-RELATED0.94positive
g10189.t1SH3 DOMAIN-CONTAINING0.94positive
g35968.t1UNCHARACTERIZED0.94positive
g16921.t1HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 442 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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