Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g22682.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g22682.t1
Gene ID Description PCC Relationship
g22682.t1BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA21positive
g14414.t1RNA HELICASE0.97positive
g14418.t1SERINE/THREONINE-PROTEIN KINASE0.96positive
g14336.t1UNCHARACTERIZED0.96positive
g2527.t1FRG1 PROTEIN0.96positive
g1080.t1RAS GTPASE-ACTIVATING PROTEINS0.95positive
g4859.t1COATOMER SUBUNIT GAMMA0.95positive
g3277.t1SUCCINYL-COA LIGASE SUBUNIT ALPHA0.95positive
g5225.t1PROTEASOME SUBUNIT ALPHA/BETA0.95positive
g11264.t1PRE-MRNA SPLICING FACTOR0.95positive
g31371.t1DULLARD PROTEIN PHOSPHATASE0.95positive
g11969.t1SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO0.95positive
g25522.t1--0.95positive
g8513.t1HOMEOBOX PROTEIN NKX0.95positive
g10110.t1--0.95positive
g26487.t1--0.94positive
g74.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1580.94positive
g35170.t1MYOSIN LIGHT CHAIN 1, 30.94positive
g27969.t1RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS0.94positive
g10504.t1--0.94positive
g6119.t1ER MEMBRANE PROTEIN COMPLEX SUBUNIT 40.94positive
g3495.t1NIBRIN-RELATED0.94positive
g34739.t1ATP-DEPENDENT RNA HELICASE RHLE-RELATED0.93positive
g16326.t1CENTROSOMAL PROTEIN 20.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 111 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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