Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g23744.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g23744.t1
Gene ID Description PCC Relationship
g23744.t1LD33804P1positive
g295.t1--0.96positive
g28027.t1FI24210P10.96positive
g3555.t1FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN0.95positive
g4160.t1--0.95positive
g6505.t1NITRIC OXIDE SYNTHASE-RELATED0.94positive
g633.t1MOLTING PROTEIN MLT-40.94positive
g8358.t1GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED0.94positive
g32018.t1--0.94positive
g29384.t1--0.94positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.94positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.94positive
g2000.t1--0.94positive
g3313.t1--0.94positive
g1424.t1--0.94positive
g4159.t1LIG_CHAN-GLU_BD DOMAIN-CONTAINING PROTEIN0.93positive
g34901.t1ACYL-COA DESATURASE0.93positive
g34024.t1LD33804P0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 78 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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