Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g2388.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g2388.t1
Gene ID Description PCC Relationship
g2388.t1HELICASE SRCAP-RELATED1positive
g2997.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.97positive
g1315.t1FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED0.96positive
g12698.t1TOPOISOMERASE II-ASSOCIATED PROTEIN PAT10.96positive
g16192.t1--0.96positive
g12080.t1LYSINE-SPECIFIC DEMETHYLASE0.96positive
g536.t1VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT0.96positive
g29391.t1--0.96positive
g17213.t1--0.96positive
g16988.t1SERINE/THREONINE-PROTEIN KINASE TAO0.96positive
g3319.t1RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 200.95positive
g27831.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.95positive
g18695.t1SYNTROPHIN0.95positive
g27562.t1E3 UBIQUITIN-PROTEIN LIGASE TRIP120.95positive
g6477.t1POLYCOMB GROUP PROTEIN0.94positive
g3318.t1--0.94positive
g18444.t1TRANSCRIPTION FACTOR ONECUT0.94positive
g8664.t1MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE0.93positive
g5570.t1NUCLEAR PROTEIN SKIP-RELATED0.93positive
g18407.t1--0.92positive
g21208.t1JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE0.91positive
g656.t1--0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 87 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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