Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g2446.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g2446.t1
Gene ID Description PCC Relationship
g2446.t1--1positive
g8055.t1BETA TRANSDUCIN-RELATED PROTEIN0.92positive
g7922.t1RP42 RELATED0.91positive
g9077.t1NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED0.90positive
g9920.t1--0.90positive
g19061.t1KH DOMAIN CONTAINING RNA BINDING PROTEIN0.89positive
g8895.t1CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS0.89positive
g1010.t1MASK PROTEIN0.89positive
g13387.t1ATF6, ISOFORM C0.89positive
g2523.t1MRNA EXPORT FACTOR AND BUB30.87positive
g3764.t1TRANSCRIPTIONAL REPRESSOR PROTEIN YY0.87positive
g3207.t1--0.87positive
g4003.t1UNCHARACTERIZED0.87positive
g2445.t1RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B0.87positive
g3742.t1PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.87positive
g6221.t1CENTROSOMAL PROTEIN OF 131 KDA0.86positive
g1840.t1ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV0.86positive
g12883.t1ACTIN0.86positive
g33420.t1CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED0.86positive
g20116.t1UNCHARACTERIZED0.86positive
g16284.t1TRANSCRIPTION INITIATION FACTOR TFIID0.84positive
g29051.t1PERICENTRIOLAR MATERIAL 1-RELATED0.83positive
g3680.t1SOLEUCYL-TRNA SYNTHETASE0.80positive
g13780.t1ZINC FINGER PROTEIN ZPR10.77positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 97 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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