Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g2452.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g2452.t1
Gene ID Description PCC Relationship
g2452.t1GOLGI SNARE BET1-RELATED1positive
g29028.t1TTC17 PROTEIN0.98positive
g14416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 580.98positive
g4845.t1PROTEIN MCM10 HOMOLOG0.98positive
g1437.t139A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL0.98positive
g406.t1--0.98positive
g11914.t1THIOESTERASE SUPERFAMILY MEMBER-RELATED0.98positive
g29628.t1EME1 PROTEIN0.98positive
g12671.t1--0.97positive
g16207.t1PROTEIN CBG266940.97positive
g12105.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED0.97positive
g7288.t1BRIDGING INTEGRATOR 30.97positive
g1064.t1MICROSOMAL PROSTAGLANDIN E SYNTHASE-20.97positive
g30320.t1--0.97positive
g27348.t1--0.97positive
g9895.t1MITOCHONDRIAL RIBOSOMAL PROTEIN S250.97positive
g9351.t1--0.97positive
g7219.t1TNF RECEPTOR ASSOCIATED FACTOR0.97positive
g5188.t1HYDROLETHALUS SYNDROME PROTEIN 10.97positive
g11993.t1NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT0.97positive
g9735.t1ATAXIN-3-RELATED0.97positive
g8443.t1IMPORTIN ALPHA0.97positive
g8042.t1TUDOR DOMAIN CONTAINING PROTEIN0.97positive
g14839.t1LIPASE0.97positive
g9376.t1METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN0.97positive
g22364.t1SIKE FAMILY MEMBER0.97positive
g18450.t1CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP70.97positive
g352.t1--0.96positive
g17935.t1NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-10.96positive
g20364.t1NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT0.96positive
g17393.t1INTERFERON ALPHA-INDUCIBLE PROTEIN 270.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 181 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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