Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g2460.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g2460.t1
Gene ID Description PCC Relationship
g2460.t1PROTEIN CBG124741positive
g11569.t1--0.97positive
g13129.t1PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.96positive
g6204.t1OLIGOPHRENIN 10.96positive
g3363.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.96positive
g24847.t1GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE0.96positive
g5956.t1KINESIN-LIKE PROTEIN KLP-30.96positive
g30946.t1--0.96positive
g13386.t1GUANINE NUCLEOTIDE EXCHANGE FACTOR0.96positive
g28119.t1RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN0.96positive
g5088.t1UNCHARACTERIZED0.96positive
g30469.t1SH3 MULTIPLE DOMAIN0.96positive
g35422.t1PROTEIN TAG-278-RELATED0.96positive
g292.t1MYB PROTEIN-RELATED0.96positive
g30992.t1ACID PHOSPHATASE-RELATED0.96positive
g1512.t1TUDOR DOMAIN CONTAINING PROTEIN0.96positive
g4833.t1CULLIN0.95positive
g3220.t1CEREBLON0.95positive
g33039.t1--0.95positive
g14376.t1UNCHARACTERIZED0.95positive
g13588.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR0.95positive
g12187.t1--0.95positive
g25023.t1VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS130.95positive
g35451.t1--0.95positive
g5015.t1SCHLAFEN0.95positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.95positive
g27562.t1E3 UBIQUITIN-PROTEIN LIGASE TRIP120.95positive
g18430.t1CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA0.95positive
g18218.t1SERINE-THREONINE PROTEIN KINASE0.95positive
g27610.t1E3 UBIQUITIN-PROTEIN LIGASE MIB20.95positive
g31417.t1CARNITINE O-ACYLTRANSFERASE0.95positive
g7539.t1GUANYL-NUCLEOTIDE EXCHANGE FACTOR0.95positive
g6427.t1UNCHARACTERIZED0.94positive
g2619.t1TRANSCRIPTION FACTOR CP20.94positive
g4965.t1UNC-13-4A, ISOFORM B0.94positive
g2565.t1RIBOSOME BINDING PROTEIN-10.94positive
g24698.t1--0.93positive
g15275.t1GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER0.93positive
g9038.t1--0.93positive
g20966.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.92positive
g12239.t1--0.92positive
g3594.t1ATP-BINDING CASSETTE SUB-FAMILY C0.92positive
g2454.t1PROTEIN PHOSPHATASE INHIBITOR0.84positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 199 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP