Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g24698.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g24698.t1
Gene ID Description PCC Relationship
g24698.t1--1positive
g11569.t1--0.94positive
g2460.t1PROTEIN CBG124740.93positive
g3244.t1LD02310P0.93positive
g12098.t1ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER0.93positive
g24697.t1LIMKAIN B LKAP0.92positive
g4965.t1UNC-13-4A, ISOFORM B0.92positive
g7247.t1OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN0.92positive
g32561.t1--0.91positive
g25023.t1VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS130.91positive
g34914.t13BP-1 RELATED RHOGAP0.91positive
g27215.t1UBIQUITIN THIOESTERASE0.91positive
g17668.t1ACETYL-COENZYME A SYNTHETASE0.91positive
g14345.t1TRANSMEMBRANE CHANNEL-RELATED0.91positive
g34221.t1ATP-BINDING CASSETTE SUB-FAMILY B0.90positive
g14712.t1--0.89positive
g9143.t1GUANYLATE BINDING PROTEIN0.89positive
g15000.t1--0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 41 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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