Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g24840.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g24840.t1
Gene ID Description PCC Relationship
g24840.t1--1positive
g192.t1COLLAGEN ALPHA0.99positive
g27468.t1SOLUTE CARRIER FAMILY 22 MEMBER0.99positive
g14669.t1COLLAGEN ALPHA0.99positive
g25713.t1--0.99positive
g25631.t1RETROTRANSPOSON0.99positive
g17124.t1EGF-LIKE DOMAIN-CONTAINING PROTEIN0.99positive
g6446.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g33383.t1IP13529P0.99positive
g13536.t1SODIUM/CALCIUM EXCHANGER0.99positive
g9043.t1METAXIN RELATED0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g9429.t1RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 10.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g5747.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.99positive
g5546.t1--0.99positive
g28150.t1--0.99positive
g6445.t1FIBRILLIN-RELATED0.99positive
g7527.t1--0.99positive
g5746.t1CRUMBS FAMILY MEMBER0.99positive
g16491.t1NADH-CYTOCHROME B5 REDUCTASE0.99positive
g24689.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.99positive
g27985.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.98positive
g3284.t1PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN0.98positive
g30473.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.98positive
g32982.t1NACHT, LRR AND CARD DOMAINS-CONTAINING0.98positive
g20650.t1D-GLUTAMATE CYCLASE, MITOCHONDRIAL0.98positive
g11499.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.98positive
g7035.t1DED DOMAIN-CONTAINING PROTEIN0.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 115 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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