Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g25716.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g25716.t1
Gene ID Description PCC Relationship
g25716.t1HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED1positive
g29901.t1--0.97positive
g21182.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.92positive
g20449.t1PROTEIN CBG238060.92positive
g3106.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.91positive
g31095.t1SI:CH211-108C17.2-RELATED-RELATED0.89positive
g34545.t1--0.88positive
g35019.t1--0.88positive
g19972.t1--0.88positive
g7175.t1--0.88positive
g5832.t1RETROTRANSPOSON0.88positive
g26072.t1--0.88positive
g35061.t1--0.88positive
g25211.t1--0.86positive
g20615.t1--0.86positive
g33326.t1--0.86positive
g10761.t1RETROTRANSPOSON0.86positive
g1409.t1--0.85positive
g27281.t1--0.84positive
g17634.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.83positive
g16706.t1--0.83positive
g28585.t1--0.82positive
g22119.t1RETROTRANSPOSON0.81positive
g34621.t1--0.80positive
g753.t1--0.80positive
g4216.t1--0.79positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 101 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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