Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g25870.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g25870.t1
Gene ID Description PCC Relationship
g25870.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED1positive
g17295.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED0.99positive
g34945.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g17836.t1-0.99positive
g19808.t1--0.99positive
g32779.t1-0.99positive
g15827.t160S RIBOSOMAL PROTEIN L3-RELATED0.99positive
g343.t1PECANEX0.99positive
g9050.t1WNT RELATED0.99positive
g24176.t1--0.99positive
g1484.t1MITOGEN-ACTIVATED PROTEIN KINASE0.99positive
g11204.t1LEUCOKININ RECEPTOR-RELATED0.99positive
g13535.t1SODIUM/CALCIUM EXCHANGER0.99positive
g12590.t1F-BOX ONLY PROTEIN 150.99positive
g34237.t1BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE0.98positive
g4719.t1PROTEIN PHOSPHATASE0.98positive
g22989.t1--0.98positive
g13814.t1ATP-BINDING CASSETTE SUB-FAMILY C0.98positive
g32571.t152 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED0.98positive
g20716.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.98positive
g2814.t1GENE, 32742-RELATED-RELATED0.98positive
g27985.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.98positive
g14085.t1CYTOCHROME P450 260.98positive
g15612.t1T-BOX PROTEIN-RELATED0.98positive
g27116.t1TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN0.98positive
g15342.t1ANKYRIN DOMAIN-CONTAINING0.98positive
g14972.t1G PROTEIN-COUPLED RECEPTOR-RELATED0.98positive
g17292.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.98positive
g32332.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.98positive
g26124.t1--0.98positive
g32036.t152 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED0.98positive
g24839.t1--0.97positive
g17957.t1NACHT, LRR AND CARD DOMAINS-CONTAINING0.97positive
g26783.t1REVERSE TRANSCRIPTASES0.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 168 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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