Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27.t1
Gene ID Description PCC Relationship
g27.t1ARYLSULFATASE1positive
g11151.t1PEPTIDASE M200.95positive
g15863.t1ARYLSULFATASE0.94positive
g21233.t1HOMOSERINE O-ACETYLTRANSFERASE0.93positive
g34965.t1VALACYCLOVIR HYDROLASE0.93positive
g27088.t1--0.93positive
g32696.t1SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 520.93positive
g6236.t1METABOTROPIC GLUTAMATE RECEPTOR0.92positive
g12833.t1ACETYL-COA C-ACETYLTRANSFERASE0.92positive
g21068.t1TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE0.92positive
g24136.t1MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER0.92positive
g15003.t1CALPAIN, SMALL SUBUNIT 1 A-RELATED0.92positive
g7306.t1HEAT SHOCK PROTEIN 70KDA0.92positive
g32578.t1TRANSLOCATION PROTEIN SEC620.92positive
g20290.t1--0.92positive
g31609.t1PEPTIDASE M200.92positive
g6705.t1TANDEM PH DOMAIN CONTAINING PROTEIN0.92positive
g30165.t1UBIQUITIN-CONJUGATING ENZYME E20.91positive
g20732.t1T7-LIKE MITOCHONDRIAL DNA HELICASE0.91positive
g28.t1ARYLSULFATASE0.91positive
g19132.t1ALDO/KETO REDUCTASE0.91positive
g13292.t1TYROSINE-PROTEIN KINASE0.91positive
g17797.t1DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED0.91positive
g27136.t1PHENYLALANYL-TRNA SYNTHETASE0.91positive
g19257.t1ADENYLYL CYCLASE-ASSOCIATED PROTEIN0.91positive
g16306.t1ANNEXIN0.91positive
g13196.t1CYTOCHROME P450 FAMILY 40.90positive
g26041.t1--0.89positive
g16756.t1LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED0.89positive
g349.t1UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL0.89positive
g3052.t1D-GLUTAMATE CYCLASE, MITOCHONDRIAL0.89positive
g27170.t1N-LINKED OLIGOSACCHARIDE PROCESSING0.87positive
g24255.t1CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A0.87positive
g12890.t1TRANSCRIPTASE, PUTATIVE-RELATED-RELATED0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 164 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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