Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27082.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27082.t1
Gene ID Description PCC Relationship
g27082.t1-1positive
g9961.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.87positive
g34553.t1--0.85positive
g27416.t1RAS GTPASE-ACTIVATING PROTEINS0.84positive
g28077.t1PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE0.84positive
g18.t1ADHESION G-PROTEIN COUPLED RECEPTOR V10.82positive
g35623.t1--0.81positive
g6267.t1MYOSIN LIGHT CHAIN 1, 30.80positive
g17233.t1VOLTAGE-GATED POTASSIUM CHANNEL0.80positive
g10455.t1MALARIA ANTIGEN-RELATED0.80positive
g22739.t1DIMETHYLANILINE MONOOXYGENASE0.80positive
g2080.t1ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE0.79positive
g27753.t1SODIUM/POTASSIUM/CALCIUM EXCHANGER0.78positive
g1969.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.78positive
g14099.t1--0.75positive
g21341.t1KETOACID-COENZYME A TRANSFERASE0.75positive
g32961.t1TRYPSIN-RELATED0.74positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 45 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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