Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27096.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27096.t1
Gene ID Description PCC Relationship
g27096.t1NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT1positive
g30885.t1TRANSMEMBRANE PROTEIN 2460.96positive
g8756.t1INSULIN GENE ENHANCER PROTEIN0.95positive
g2906.t1GRPE PROTEIN0.95positive
g9468.t1--0.95positive
g10132.t1BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE0.95positive
g35722.t1NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.20.95positive
g13661.t1CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT0.94positive
g23527.t1NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED0.94positive
g2217.t1NUDIX HYDROLASE RELATED0.94positive
g1312.t1GOLGI REASSEMBLY STACKING PROTEIN GRASP0.94positive
g13841.t1ZGC:1951700.94positive
g24804.t1--0.94positive
g911.t1KRUEPPEL-LIKE TRANSCRIPTION FACTOR0.94positive
g32287.t1GLR0591 PROTEIN0.94positive
g12850.t1--0.93positive
g23363.t1COILED-COIL ALPHA-HELICAL ROD PROTEIN 10.93positive
g13897.t1--0.80positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 58 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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