Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27457.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27457.t1
Gene ID Description PCC Relationship
g27457.t1HYCCIN RELATED1positive
g16595.t1CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED0.93positive
g20698.t1GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-20.93positive
g5575.t1DNA2/NAM7 HELICASE FAMILY0.92positive
g13307.t1ALDEHYDE DEHYDROGENASE0.92positive
g15704.t1OXA10.92positive
g28692.t1CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 20.92positive
g24704.t1GLUTAMINE-TRNA LIGASE0.92positive
g604.t1ENDOPLASMIC RETICULUM RESIDENT PROTEIN 440.92positive
g28600.t1CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED0.92positive
g18664.t1ALANINE AMINOTRANSFERASE0.92positive
g8730.t1RAB GTPASE-ACTIVATING PROTEIN 1-LIKE0.92positive
g3716.t1MITOCHONDRIA-EATING PROTEIN-RELATED0.92positive
g15860.t1DNA REPAIR/RNA PROCESSING CPSF FAMILY0.91positive
g27393.t1TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT0.91positive
g15035.t1DISCS LARGE0.91positive
g24668.t1SERINE/THREONINE-PROTEIN KINASE0.90positive
g21348.t1MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK0.90positive
g877.t1ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE0.89positive
g26613.t1--0.77positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 95 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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