Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27740.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27740.t1
Gene ID Description PCC Relationship
g27740.t1DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED1positive
g27061.t1RAB GDP-DISSOCIATION INHIBITOR0.96positive
g1428.t1BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR0.96positive
g23789.t1MALATE SYNTHASE0.96positive
g11655.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 120.96positive
g35047.t1GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN0.96positive
g23603.t1SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO0.96positive
g7559.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.96positive
g17122.t1NUCLEOLAR PROTEIN 80.96positive
g4065.t1LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED0.96positive
g21418.t1ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED0.96positive
g2885.t1TYROSINE-PROTEIN KINASE0.96positive
g23413.t1FORMIN-BINDING PROTEIN 40.96positive
g27347.t1PROTEIN CBG162000.96positive
g27414.t1CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED0.95positive
g18490.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.95positive
g16765.t1PHOSPHATIDYLCHOLINE TRANSFER PROTEIN0.95positive
g12078.t1TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER0.95positive
g6872.t1ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE0.95positive
g31411.t1TNF RECEPTOR ASSOCIATED FACTOR0.95positive
g35490.t1DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED0.95positive
g6321.t1PROTEASE M14 CARBOXYPEPTIDASE0.95positive
g30044.t1ARGININE-TRNA-PROTEIN TRANSFERASE 10.94positive
g5348.t1E3 UBIQUITIN-PROTEIN LIGASE PRAJA0.94positive
g28720.t1LD33804P0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 90 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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