Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27897.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27897.t1
Gene ID Description PCC Relationship
g27897.t1ELECTRON TRANSFER FLAVOPROTEIN ALPHA1positive
g11030.t1ENOLASE0.96positive
g12606.t1ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL0.95positive
g12238.t1FI01416P0.94positive
g8390.t1MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED0.94positive
g2234.t1DISULFIDE OXIDOREDUCTASE0.94positive
g11884.t1-0.93positive
g10031.t1MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 10.93positive
g521.t1TETRA THYMOSIN0.92positive
g29029.t1UNCHARACTERIZED0.92positive
g2079.t1UBIQUITIN-CONJUGATING ENZYME E20.92positive
g15083.t1NUCLEOSIDE DIPHOSPHATE KINASE0.92positive
g1020.t1NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT0.91positive
g11062.t1PIERCE HOMOLOG0.91positive
g9924.t1L 2 012890.91positive
g14604.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 30.91positive
g35048.t1ENOYL-COA HYDRATASE-RELATED0.90positive
g11647.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 130.90positive
g17405.t1ATP SYNTHASE DELTA CHAIN0.90positive
g27309.t1SHORT-CHAIN DEHYDROGENASE/REDUCTASE0.89positive
g28417.t1N-MYC DOWNSTREAM REGULATED0.89positive
g21457.t1SEC100.89positive
g29718.t1S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN0.89positive
g3103.t1CYTOCHROME C OXIDASE SUBUNIT 6B0.89positive
g11956.t1ATP-DEPENDENT RNA HELICASE DBP30.88positive
g11202.t18-OXOGUANINE DNA GLYCOSYLASE0.88positive
g16926.t1UNCHARACTERIZED0.87positive
g34851.t1TRANSMEMBRANE PROTEIN 2320.87positive
g7549.t1FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED0.87positive
g9639.t1--0.87positive
g6828.t1FLAGELLAR RADIAL SPOKE PROTEIN 30.85positive
g7430.t1--0.82positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 223 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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