Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g27945.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g27945.t1
Gene ID Description PCC Relationship
g27945.t1--1positive
g10112.t1CENTROSOMAL PROTEIN 21.00positive
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g7147.t1KREMEN PROTEIN0.99positive
g18965.t1CARBOHYDRATE SULFOTRANSFERASE0.99positive
g3335.t1--0.99positive
g21558.t1I[[H]] CHANNEL, ISOFORM E0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g1886.t1PROPERDIN0.99positive
g4437.t1--0.99positive
g3364.t1GUANYLYL CYCLASE0.99positive
g15545.t1--0.99positive
g34719.t1OPSIN0.99positive
g9837.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g32539.t1--0.99positive
g11099.t1--0.99positive
g3385.t1NOTCH LIGAND FAMILY MEMBER0.99positive
g26779.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g17098.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g11889.t1PROSTAGLANDIN G/H SYNTHASE0.99positive
g8334.t1--0.99positive
g29047.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g29503.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 600.99positive
g7720.t1AMINO ACID TRANSPORTER0.99positive
g627.t1--0.99positive
g170.t1--0.99positive
g4055.t1--0.99positive
g17486.t1--0.99positive
g14255.t1AQUAPORIN TRANSPORTER0.99positive
g10567.t1ADENOSYLHOMOCYSTEINASE0.99positive
g14021.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g27522.t1ACYL-MALONYL CONDENSING ENZYME-RELATED0.99positive
g6786.t1--0.99positive
g3870.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED0.99positive
g12791.t1SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN0.99positive
g3893.t1--0.99positive
g12229.t1--0.99positive
g9921.t1UNCHARACTERIZED0.99positive
g1846.t1--0.98positive
g22721.t1PROSTAGLANDIN G/H SYNTHASE0.98positive
g5521.t1--0.98positive
g19981.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.98positive
g16807.t1--0.98positive
g27586.t1HOMEOBOX PROTEIN SIX0.98positive
g22927.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g29914.t1BETA-1,4-GALACTOSYLTRANSFERASE0.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 263 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP