Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28015.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28015.t1
Gene ID Description PCC Relationship
g28015.t1RHO FAMILY GTPASE1positive
g9464.t1CADHERIN-230.97positive
g560.t1--0.96positive
g23806.t1VOLTAGE-GATED POTASSIUM CHANNEL0.95positive
g362.t1METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN0.95positive
g2902.t1HOMEOBOX PROTEIN TRANSCRIPTION FACTORS0.95positive
g3299.t1REGULATORY-ASSOCIATED PROTEIN OF MTOR0.95positive
g3345.t13-5 EXONUCLEASE0.95positive
g10197.t1INHIBITOR OF APOPTOSIS0.94positive
g16627.t1EPSIN/ENT-RELATED0.94positive
g8067.t1MAP/MICROTUBULE AFFINITY-REGULATING KINASE0.94positive
g6655.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.94positive
g3237.t1INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED0.94positive
g15001.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.94positive
g12598.t1T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL0.94positive
g14204.t1MYELIN TRANSCRIPTION FACTOR 1-RELATED0.93positive
g12373.t1SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED0.93positive
g35457.t1RNA HELICASE0.93positive
g28086.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.93positive
g3205.t1TRANSCRIPTIONAL ADAPTER 3-RELATED0.93positive
g509.t1AMINOMETHYLTRANSFERASE0.93positive
g6476.t1PHD/F-BOX CONTAINING PROTEIN0.93positive
g4897.t1CRUMBS FAMILY MEMBER0.93positive
g3599.t1--0.93positive
g13656.t1NUCLEOBINDIN0.93positive
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 10.93positive
g9699.t1CARBOHYDRATE SULFOTRANSFERASE0.92positive
g30370.t1GLR0591 PROTEIN0.92positive
g7212.t1RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN0.92positive
g17256.t1--0.91positive
g20967.t1REGULATOR-RELATED0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 143 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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