Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28027.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28027.t1
Gene ID Description PCC Relationship
g28027.t1FI24210P11positive
g29384.t1--0.98positive
g6505.t1NITRIC OXIDE SYNTHASE-RELATED0.98positive
g295.t1--0.98positive
g9738.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.97positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.97positive
g7431.t1--0.97positive
g12341.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.97positive
g3586.t1NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 10.97positive
g15081.t1-0.97positive
g2000.t1--0.97positive
g8358.t1GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED0.97positive
g23743.t1LD33804P0.97positive
g9525.t1-0.97positive
g11138.t1BANK1/PIK3AP1 FAMILY MEMBER0.97positive
g633.t1MOLTING PROTEIN MLT-40.97positive
g4500.t1RIKEN CDNA 9930021J03 GENE0.97positive
g5326.t1D-GLUCURONYL C5-EPIMERASE0.96positive
g27269.t1ZINC FINGER PROTEIN0.96positive
g4160.t1--0.96positive
g11633.t1TRANSCRIPTIONAL ADAPTER 10.96positive
g9295.t1STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED0.96positive
g2191.t1RUBY-EYE2-LIKE PROTEIN0.96positive
g3555.t1FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN0.96positive
g4334.t1--0.96positive
g16482.t1S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED0.96positive
g5277.t1HISTONE-LYSINE N-METHYLTRANSFERASE SMYD0.96positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.96positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.96positive
g23744.t1LD33804P0.96positive
g6210.t1METHYLMALONYL-COA MUTASE0.96positive
g27755.t1HOMER0.96positive
g5791.t1PLACENTAL PROTEIN 60.96positive
g23138.t1UBIQUITIN SPECIFIC PROTEINASE0.95positive
g4159.t1LIG_CHAN-GLU_BD DOMAIN-CONTAINING PROTEIN0.95positive
g920.t1FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I0.95positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.95positive
g27861.t1CENTROSOMAL PROTEIN OF 170 KDA0.95positive
g31915.t1--0.95positive
g19595.t1IP01015P-RELATED0.95positive
g4902.t1--0.95positive
g3313.t1--0.95positive
g12272.t1SERINE/THREONINE-PROTEIN KINASE 170.95positive
g4266.t1--0.95positive
g27754.t1HOMER0.95positive
g17232.t1MYOTROPHIN0.94positive
g12233.t1--0.94positive
g12322.t1LEUCINE RICH REPEAT PROTEIN0.94positive
g11253.t1DYNEIN INTERMEDIATE CHAIN0.94positive
g35274.t1SARCOSINE DEHYDROGENASE-RELATED0.94positive
g15180.t1SERINE-THREONINE PROTEIN KINASE0.93positive
g19451.t1GLYCOGENIN SUBFAMILY MEMBER0.92positive
g8086.t15-HYDROXYTRYPTAMINE RECEPTOR0.88positive
g10570.t1POLYCYSTIN-10.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 407 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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