Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28082.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28082.t1
Gene ID Description PCC Relationship
g28082.t1PERIODIC TRYPTOPHAN PROTEIN 11positive
g99.t1POLY ADP-RIBOSE GLYCOHYDROLASE0.96positive
g14336.t1UNCHARACTERIZED0.94positive
g27368.t1UNCHARACTERIZED0.93positive
g4790.t1NUCLEOLAR GTP-BINDING PROTEIN 10.93positive
g27456.t1--0.92positive
g3908.t1RING FINGER PROTEIN-RELATED0.92positive
g1080.t1RAS GTPASE-ACTIVATING PROTEINS0.92positive
g26105.t1UNCHARACTERIZED0.92positive
g11264.t1PRE-MRNA SPLICING FACTOR0.91positive
g28263.t1NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED0.91positive
g15387.t150S RIBOSOMAL PROTEIN L150.91positive
g3060.t1-0.91positive
g28409.t1F-BOX ONLY PROTEIN 30.91positive
g25529.t1--0.90positive
g30848.t1CWF19, CELL CYCLE CONTROL PROTEIN0.90positive
g5520.t1--0.89positive
g28890.t1PROTEIN MIS12 HOMOLOG0.89positive
g19260.t1GEO13361P1-RELATED0.88positive
g15599.t1--0.88positive
g8343.t1SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC110.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 60 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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