Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28278.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28278.t1
Gene ID Description PCC Relationship
g28278.t1CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE1positive
g13349.t1HEAT SHOCK 70 KDA PROTEIN 140.93positive
g27566.t1--0.93positive
g2032.t1MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B0.93positive
g8588.t1--0.93positive
g31427.t1AGAP008221-PA0.92positive
g1012.t1VANG-LIKE PROTEIN0.92positive
g11874.t1CYCLINS0.92positive
g129.t1OLIGOPEPTIDE TRANSPORTER-RELATED0.92positive
g27695.t1AMINOTRANSFERASE0.92positive
g11918.t1AAA DOMAIN-CONTAINING0.92positive
g10507.t1ECTO-NOX DISULFIDE-THIOL EXCHANGER0.92positive
g32641.t1--0.92positive
g27240.t1DENN DOMAIN-CONTAINING0.92positive
g33640.t1--0.91positive
g9811.t1LYMPHOID-SPECIFIC HELICASE0.91positive
g28285.t1DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE0.91positive
g15453.t1TNF RECEPTOR ASSOCIATED FACTOR0.91positive
g18638.t1TRANSMEMBRANE GTPASE FZO10.89positive
g26776.t1BONUS, ISOFORM C-RELATED0.85positive
g14783.t1FATTY ACID ACYL TRANSFERASE-RELATED0.78positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 82 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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