Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28587.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28587.t1
Gene ID Description PCC Relationship
g28587.t1CARNITINE O-ACYLTRANSFERASE1positive
g4241.t1--0.96positive
g7773.t1TYROSINE-PROTEIN KINASE RECEPTOR0.96positive
g20375.t1--0.96positive
g34880.t1ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 10.96positive
g15137.t1--0.96positive
g34944.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.96positive
g4959.t1KRUEPPEL-LIKE TRANSCRIPTION FACTOR0.96positive
g17343.t1TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN0.95positive
g16496.t1LD33804P0.95positive
g30175.t1--0.95positive
g6524.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.95positive
g7815.t1SIMILAR TO HYPOTHETICAL PROTEIN FLJ402980.95positive
g444.t1PR DOMAIN ZINC FINGER PROTEIN0.95positive
g7694.t1TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS0.94positive
g6163.t1PROTEIN CEBPZOS0.94positive
g5414.t1LIPID PHOSPHATE PHOSPHATASE0.94positive
g15093.t1NETRIN/LAMININ-RELATED0.93positive
g29496.t1AGAP001331-PA-RELATED0.93positive
g10773.t1--0.92positive
g25079.t1--0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 81 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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