Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g28740.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g28740.t1
Gene ID Description PCC Relationship
g28740.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN1positive
g12379.t1--0.99positive
g2177.t1--0.99positive
g34947.t1--0.99positive
g34829.t1--0.99positive
g10500.t1PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED0.99positive
g24505.t1DUF946 FAMILY PROTEIN0.98positive
g35051.t1--0.98positive
g35021.t1CRUMBS FAMILY MEMBER0.98positive
g14588.t1TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR0.98positive
g5427.t1DNAJ PROTEIN ERDJ3A0.98positive
g3937.t1--0.98positive
g22951.t1NEUROTRANSMITTER GATED ION CHANNEL0.98positive
g35145.t1PENTRAXIN0.98positive
g12607.t1UDP-GLUCOSE 4-EPIMERASE0.98positive
g13325.t1RETICULOCALBIN0.98positive
g10586.t1--0.98positive
g20268.t1--0.98positive
g17459.t1OXIDASE/PEROXIDASE0.98positive
g33002.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED0.98positive
g2016.t1ETS0.98positive
g19360.t1--0.98positive
g12994.t1--0.98positive
g195.t1TESTIS-EXPRESSED PROTEIN 470.98positive
g23758.t1--0.98positive
g13514.t1--0.97positive
g16799.t1KH DOMAIN CONTAINING RNA BINDING PROTEIN0.97positive
g9863.t1--0.97positive
g12967.t1--0.97positive
g11640.t1RETICULOCALBIN0.97positive
g5579.t1--0.97positive
g1734.t15-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE0.96positive
g18409.t1--0.96positive
g7357.t1--0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 170 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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