Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g29577.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g29577.t1
Gene ID Description PCC Relationship
g29577.t1NINEIN1positive
g7240.t1--0.95positive
g14084.t1CYTOCHROME P450 260.95positive
g3887.t1F-BOX ONLY PROTEIN 150.94positive
g4695.t1SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN0.94positive
g11575.t1TRANSPORTIN 3 AND IMPORTIN 130.94positive
g4051.t1TNF RECEPTOR ASSOCIATED FACTOR0.94positive
g27594.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED0.94positive
g5653.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1810.94positive
g22684.t1BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA20.94positive
g9391.t1PEPTIDYL-PROLYL CIS-TRANS ISOMERASE0.94positive
g8236.t1BETA-CAROTENE DIOXYGENASE0.94positive
g13360.t1PRESEQUENCE PROTEASE0.93positive
g29995.t1CAMK FAMILY PROTEIN KINASE0.93positive
g25373.t1--0.93positive
g35156.t1C2 DOMAIN-CONTAINING PROTEIN 50.93positive
g10733.t1GRB10 INTERACTING GYF PROTEIN0.93positive
g16775.t1SHC TRANSFORMING PROTEIN0.92positive
g14687.t1FIDIPIDINE0.92positive
g1618.t1DYNACTIN 1-RELATED MICROTUBULE-BINDING0.92positive
g20291.t1CAMK FAMILY PROTEIN KINASE0.92positive
g29576.t1--0.92positive
g29722.t1GLUTAMINE-TRNA LIGASE0.91positive
g6585.t1--0.89positive
g14041.t1IMPORTIN BETA0.89positive
g14044.t1LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED0.82positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 82 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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