Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g30241.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g30241.t1
Gene ID Description PCC Relationship
g30241.t1PROTEIN C21ORF591positive
g10969.t1SAM DOMAIN-CONTAINING PROTEIN-RELATED0.98positive
g16799.t1KH DOMAIN CONTAINING RNA BINDING PROTEIN0.98positive
g25442.t1CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 700.97positive
g1456.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED0.97positive
g17860.t1DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 10.97positive
g28231.t1KPL2-RELATED0.97positive
g2862.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 320.97positive
g12745.t1REGULATOR OF G-PROTEIN SIGNALING 220.97positive
g7816.t1DRAB11-RELATED0.97positive
g7704.t1LUNG ADENOMA SUSCEPTIBILITY 1-RELATED0.97positive
g3302.t1IQ DOMAIN-CONTAINING PROTEIN K0.97positive
g3531.t1ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 120.97positive
g10451.t1WD-40 REPEAT PROTEIN0.97positive
g18613.t1LEUCINE-RICH REPEAT-CONTAINING PROTEIN 340.97positive
g723.t1ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 10.97positive
g28180.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.96positive
g35077.t1PAXILLIN-RELATED0.96positive
g7528.t1UNCHARACTERIZED0.96positive
g2216.t1--0.96positive
g6732.t1--0.96positive
g6280.t1CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 2210.95positive
g16924.t1WD40 REPEAT DOMAIN 950.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 72 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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