Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g30393.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g30393.t1
Gene ID Description PCC Relationship
g30393.t1IMPORTIN BETA1positive
g12828.t1IMPORTIN BETA0.98positive
g1315.t1FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED0.96positive
g24302.t1--0.96positive
g536.t1VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT0.96positive
g14612.t1TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER0.96positive
g6477.t1POLYCOMB GROUP PROTEIN0.96positive
g4488.t1REMODELING AND SPACING FACTOR 10.95positive
g2371.t1CALCIUM-TRANSPORTING ATPASE0.95positive
g5570.t1NUCLEAR PROTEIN SKIP-RELATED0.95positive
g3049.t1ATP SYNTHASE GAMMA-RELATED0.94positive
g27768.t1--0.94positive
g20712.t1TUDOR DOMAIN CONTAINING PROTEIN0.94positive
g4806.t1KELCH PROTEIN0.93positive
g30392.t1ISLET CELL AUTOANTIGEN 10.93positive
g27831.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.93positive
g29392.t1SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED0.91positive
g29231.t1--0.91positive
g656.t1--0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 65 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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