Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g308.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g308.t1
Gene ID Description PCC Relationship
g308.t1CENTROSOMAL PROTEIN KIZUNA1positive
g5217.t1FORMIN HOMOLOGY 2 FAMILY MEMBER0.93positive
g6625.t1TRANSCRIPTION FACTOR-LIKE 5 PROTEIN0.92positive
g21382.t1DNA2/NAM7 HELICASE FAMILY0.92positive
g5617.t1CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS0.92positive
g16274.t1POLY [ADP-RIBOSE] POLYMERASE0.91positive
g21193.t1ZINC FINGER, ZZ TYPE0.91positive
g11304.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.91positive
g23617.t1--0.91positive
g20115.t1UNCHARACTERIZED0.91positive
g14350.t1SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN0.91positive
g23371.t1--0.90positive
g10316.t1--0.90positive
g35594.t1DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT0.90positive
g30116.t1G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP0.90positive
g14967.t1MRNA-CAPPING ENZYME0.90positive
g23726.t1FACIOGENITAL DYSPLASIA PROTEIN0.89positive
g5643.t1PR DOMAIN ZINC FINGER PROTEIN0.89positive
g17991.t1UNCHARACTERIZED0.89positive
g13534.t1AHD DOMAIN-CONTAINING PROTEIN0.88positive
g3272.t1UROCANATE HYDRATASE0.88positive
g6764.t1PEPTIDYL-PROLYL CIS-TRANS ISOMERASE0.88positive
g34910.t1MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B0.87positive
g8895.t1CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS0.87positive
g23704.t1SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED0.87positive
g20114.t1--0.87positive
g10555.t1NUCLEOPORIN NUP37 P37 -RELATED0.86positive
g17798.t1PEPTIDASE S9 PROLYL OLIGOPEPTIDASE0.85positive
g3206.t1--0.85positive
g23458.t1--0.85positive
g19309.t1--0.84positive
g31796.t1GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING0.79positive
g22671.t1--0.71positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 140 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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