Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g30946.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g30946.t1
Gene ID Description PCC Relationship
g30946.t1--1positive
g11201.t1PA-PL1 PHOSPHOLIPASE FAMILY0.98positive
g35422.t1PROTEIN TAG-278-RELATED0.98positive
g30043.t1SARCOMA ANTIGEN NY-SAR-95-RELATED0.98positive
g18793.t1MULTIVESICULAR BODY SUBUNIT 12A0.98positive
g4097.t1--0.97positive
g17213.t1--0.97positive
g27562.t1E3 UBIQUITIN-PROTEIN LIGASE TRIP120.97positive
g35122.t1ZGC:1132080.97positive
g6204.t1OLIGOPHRENIN 10.97positive
g9758.t1--0.97positive
g1512.t1TUDOR DOMAIN CONTAINING PROTEIN0.97positive
g12187.t1--0.97positive
g943.t1HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED0.97positive
g3319.t1RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 200.97positive
g2090.t1SIT4 YEAST -ASSOCIATING PROTEIN-RELATED0.97positive
g28024.t1HSC70CB, ISOFORM G-RELATED0.97positive
g5956.t1KINESIN-LIKE PROTEIN KLP-30.97positive
g9195.t1RGS-GAIP INTERACTING PROTEIN GIPC0.97positive
g17899.t1AGAP011572-PA0.97positive
g9206.t1YTH YT521-B HOMOLOGY DOMAIN-CONTAINING0.97positive
g13996.t1SYNTENIN RELATED0.96positive
g16883.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.96positive
g18191.t1RUVB-RELATED REPTIN AND PONTIN0.96positive
g12548.t1HECT DOMAIN UBIQUITIN-PROTEIN LIGASE0.96positive
g5015.t1SCHLAFEN0.96positive
g14879.t1TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA0.96positive
g2460.t1PROTEIN CBG124740.96positive
g18431.t1PUTATIVE ATP-ASE0.96positive
g21924.t1RE40534P-RELATED0.96positive
g2072.t1OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN0.96positive
g13386.t1GUANINE NUCLEOTIDE EXCHANGE FACTOR0.96positive
g5631.t1GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-20.96positive
g14376.t1UNCHARACTERIZED0.95positive
g30992.t1ACID PHOSPHATASE-RELATED0.95positive
g3363.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.95positive
g19547.t1AGAP001623-PA0.95positive
g24847.t1GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE0.95positive
g2997.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.95positive
g8344.t1SIN3B-RELATED0.95positive
g292.t1MYB PROTEIN-RELATED0.95positive
g21307.t1PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN0.95positive
g18218.t1SERINE-THREONINE PROTEIN KINASE0.95positive
g32067.t1--0.95positive
g9294.t1GTP CYCLOHYDROLASE I0.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 322 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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