Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3095.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3095.t1
Gene ID Description PCC Relationship
g3095.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED1positive
g11711.t1BATTENIN0.99positive
g27357.t1-0.98positive
g9738.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.98positive
g12755.t1--0.98positive
g16839.t1WD REPEAT AND COILED-COIL-CONTAINING PROTEIN0.98positive
g17147.t1--0.98positive
g11633.t1TRANSCRIPTIONAL ADAPTER 10.98positive
g15363.t1RIBONUCLEASE0.98positive
g1835.t1ANOCTAMIN0.98positive
g20275.t1TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 30.97positive
g5277.t1HISTONE-LYSINE N-METHYLTRANSFERASE SMYD0.97positive
g33312.t1KELCH PROTEIN0.97positive
g4804.t1FACTOR VIII-ASSOCIATED GENE 10.97positive
g11138.t1BANK1/PIK3AP1 FAMILY MEMBER0.97positive
g16482.t1S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED0.97positive
g22068.t1BONUS, ISOFORM C-RELATED0.97positive
g11552.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.97positive
g27270.t1BOULE-RELATED0.97positive
g11776.t1PR DOMAIN ZINC FINGER PROTEIN0.97positive
g12333.t1SI:DKEY-16J16.40.97positive
g11629.t1KNIRPS-RELATED PROTEIN-RELATED0.97positive
g6207.t1--0.97positive
g2562.t1-0.97positive
g12295.t1POLYCOMB GROUP PROTEIN0.97positive
g16919.t1ES-2 PROTEIN - RELATED0.97positive
g6430.t1SWAP-70 RECOMBINASE0.97positive
g35727.t1UNCHARACTERIZED0.97positive
g34190.t1--0.97positive
g9511.t1--0.97positive
g878.t1CENTROMERE PROTEIN P0.96positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.96positive
g4500.t1RIKEN CDNA 9930021J03 GENE0.96positive
g18371.t1DELTEX-RELATED0.96positive
g15757.t1UNCHARACTERIZED0.96positive
g22788.t1SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC0.96positive
g23745.t1LD33804P0.96positive
g30205.t1RAB GDP/GTP EXCHANGE FACTOR0.96positive
g1978.t1ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER0.96positive
g2354.t1--0.96positive
g9295.t1STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED0.96positive
g12364.t1FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 1000.96positive
g17146.t1SORTING NEXIN-29-RELATED0.95positive
g28159.t1OS05G0565100 PROTEIN0.95positive
g18946.t1--0.95positive
g22353.t1PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED0.95positive
g4552.t1F-BOX/WD REPEAT-CONTAINING PROTEIN 20.95positive
g1032.t1ALCOHOL DEHYDROGENASE0.94positive
g17945.t1--0.94positive
g32022.t1DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER0.94positive
g3313.t1--0.94positive
g7497.t1CULTURE SPECIFIC PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00130)-RELATED0.94positive
g3633.t1LEUCOKININ RECEPTOR-RELATED0.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 447 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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