Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3207.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3207.t1
Gene ID Description PCC Relationship
g3207.t1--1positive
g27171.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.93positive
g17456.t1BCS1 AAA-TYPE ATPASE0.92positive
g13387.t1ATF6, ISOFORM C0.92positive
g13688.t1UNCHARACTERIZED0.91positive
g2523.t1MRNA EXPORT FACTOR AND BUB30.90positive
g1399.t1TGF-BETA FAMILY0.90positive
g1782.t1PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 10.89positive
g5047.t1C2H2 ZINC FINGER CGI-62-RELATED0.89positive
g305.t1--0.89positive
g8895.t1CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS0.89positive
g3898.t1MDM2-BINDING PROTEIN0.88positive
g1541.t1UNCHARACTERIZED0.88positive
g4966.t1PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED0.88positive
g27813.t1E3 UBIQUITIN-PROTEIN LIGASE TRIM370.88positive
g9919.t1SOLUTE CARRIER FAMILY 250.88positive
g5643.t1PR DOMAIN ZINC FINGER PROTEIN0.88positive
g35003.t1KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED0.87positive
g2446.t1--0.87positive
g7922.t1RP42 RELATED0.87positive
g28265.t1SER/THR-PROTEIN KINASE RIO20.86positive
g27760.t1--0.86positive
g1840.t1ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV0.86positive
g9920.t1--0.86positive
g13187.t1CENTAURIN/ARF0.85positive
g30567.t1BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED0.85positive
g14086.t1HEPARAN SULFATE 2-O-SULFOTRANSFERASE0.85positive
g6221.t1CENTROSOMAL PROTEIN OF 131 KDA0.84positive
g20116.t1UNCHARACTERIZED0.84positive
g12631.t1--0.80positive
g18161.t1VILLIN0.80positive
g18933.t1--0.80positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 174 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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