Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g32416.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g32416.t1
Gene ID Description PCC Relationship
g32416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1581positive
g22787.t1ROTATIN0.97positive
g14195.t1V-TYPE ATP SYNTHASE SUBUNIT D0.97positive
g7552.t1RHO-TYPE GTPASE ACTIVATING PROTEIN0.96positive
g3592.t1SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA0.96positive
g24339.t1PRE-MRNA SPLICING FACTOR0.96positive
g14500.t1PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE0.96positive
g35490.t1DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED0.96positive
g11298.t1RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG0.95positive
g27944.t1CENTROMERE/KINETOCHORE PROTEIN ZW100.95positive
g7350.t1PERICENTRIN-LIKE PROTEIN, ISOFORM F0.95positive
g20194.t1TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP10.95positive
g23603.t1SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO0.95positive
g12582.t1NUCLEOREDOXIN0.95positive
g12735.t1GOLGI MEMBRANE PROTEIN YIP10.95positive
g29170.t1GTP-BINDING PROTEIN-RELATED0.95positive
g2437.t1TRANSMEMBRANE PROTEIN 1010.95positive
g12563.t1NUCLEAR PORE COMPLEX PROTEIN NUP2050.95positive
g5255.t1ACTIN0.94positive
g18490.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.94positive
g14797.t1ATP-BINDING TRANSPORT PROTEIN-RELATED0.94positive
g27629.t1LD35087P0.94positive
g34679.t1COLLAGEN ALPHA0.94positive
g9273.t1TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED0.94positive
g4697.t1PROLYL 4-HYDROXYLASE ALPHA SUBUNIT0.94positive
g12970.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.93positive
g9379.t1NUCLEAR PORE COMPLEX PROTEIN NUP1600.93positive
g2622.t1DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER0.93positive
g10450.t1WD REPEAT-CONTAINING PROTEIN POP10.93positive
g10821.t1--0.89positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 142 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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