Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g32435.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g32435.t1
Gene ID Description PCC Relationship
g32435.t1ENOLASE (DUF1399)1positive
g11979.t1--0.92positive
g18077.t1PROTEIN CBG266940.90positive
g23632.t1RETROTRANSPOSON0.89positive
g16750.t1--0.89positive
g21474.t1--0.86positive
g33326.t1--0.86positive
g23986.t1L1 TRANSPOSABLE ELEMENT-RELATED0.85positive
g21978.t1MYND-TYPE DOMAIN-CONTAINING PROTEIN0.85positive
g32712.t1--0.85positive
g2380.t1REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN0.85positive
g15071.t1PROTEIN CBG266940.84positive
g33497.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.83positive
g9761.t1RETROTRANSPOSON0.83positive
g1409.t1--0.83positive
g28671.t1UNCHARACTERIZED0.83positive
g16223.t1--0.83positive
g35383.t1--0.82positive
g23181.t1--0.82positive
g12140.t1C2H2-TYPE DOMAIN-CONTAINING PROTEIN0.82positive
g32515.t1REVERSE TRANSCRIPTASES0.81positive
g23214.t1--0.81positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 64 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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