Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g32453.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g32453.t1
Gene ID Description PCC Relationship
g32453.t1--1positive
g6532.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 870.97positive
g35035.t1OXYSTEROL-BINDING PROTEIN-RELATED0.96positive
g4778.t1CELL DIVISION PROTEIN KINASE0.96positive
g27203.t1WD40 REPEAT PROTEIN0.96positive
g10452.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.95positive
g28014.t1SERINE-THREONINE PROTEIN KINASE0.95positive
g27195.t1--0.95positive
g8857.t1AGAP004327-PA0.95positive
g23802.t1--0.95positive
g18377.t1THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED0.95positive
g27894.t1HISTIDINE TRIAD HIT PROTEIN0.94positive
g3368.t1POLYKETIDE SYNTHASE-RELATED0.94positive
g15492.t1DDRGK DOMAIN-CONTAINING PROTEIN 10.94positive
g33158.t1ZGC:1582600.94positive
g635.t11-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED0.94positive
g20918.t1PECANEX0.94positive
g16277.t1SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN0.94positive
g4157.t1LOC3611920.93positive
g6144.t1E3 UBIQUITIN-PROTEIN LIGASE UBR70.93positive
g34589.t1--0.93positive
g27137.t1--0.93positive
g15020.t1PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL0.93positive
g2792.t1HOMEOBOX PROTEIN NKX0.92positive
g31858.t1CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 990.91positive
g34704.t1FERRITIN0.89positive
g2780.t1BUCENTAUR RELATED0.71positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 141 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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