Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g32455.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g32455.t1
Gene ID Description PCC Relationship
g32455.t1--1positive
g11857.t1HOMEOBOX PROTEIN NKX1.00positive
g12874.t1HOMEOBOX PROTEIN NKX0.99positive
g22127.t1HOMEOBOX PROTEIN NKX0.99positive
g8374.t1ACTIVATOR OF S-PHASE KINASE-RELATED0.98positive
g8339.t1--0.97positive
g21084.t1TRANSLATION FACTOR GUF1-RELATED0.96positive
g27242.t1UNCHARACTERIZED0.96positive
g1243.t1TOLL-LIKE RECEPTOR0.96positive
g2794.t1HOMEOBOX PROTEIN NKX0.95positive
g16665.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.95positive
g30521.t1--0.95positive
g25675.t1--0.95positive
g3660.t1--0.95positive
g28257.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED0.95positive
g1478.t1--0.94positive
g28727.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.94positive
g10189.t1SH3 DOMAIN-CONTAINING0.94positive
g28274.t1--0.94positive
g568.t1--0.93positive
g22066.t1--0.93positive
g35968.t1UNCHARACTERIZED0.93positive
g24189.t1PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED0.93positive
g14019.t1--0.92positive
g12873.t1--0.92positive
g9530.t1FIBROBLAST GROWTH FACTOR0.92positive
g967.t1CENTROSOMAL PROTEIN OF 290 KDA0.92positive
g14675.t1--0.90positive
g251.t1--0.90positive
g34142.t1--0.90positive
g33321.t1--0.89positive
g27430.t1G PROTEIN-COUPLED RECEPTOR0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 188 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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