Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3297.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3297.t1
Gene ID Description PCC Relationship
g3297.t1PERFORIN-LIKE PROTEIN 11positive
g2374.t1PROTEIN FAM220A0.86positive
g13534.t1AHD DOMAIN-CONTAINING PROTEIN0.86positive
g1541.t1UNCHARACTERIZED0.85positive
g16274.t1POLY [ADP-RIBOSE] POLYMERASE0.84positive
g5643.t1PR DOMAIN ZINC FINGER PROTEIN0.84positive
g15353.t1UBIQUITIN-CONJUGATING ENZYME E20.83positive
g10964.t1LYSYL ENDOPEPTIDASE0.83positive
g305.t1--0.83positive
g2190.t1DNA-DIRECTED RNA POLYMERASE0.82positive
g17456.t1BCS1 AAA-TYPE ATPASE0.82positive
g1840.t1ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV0.82positive
g20116.t1UNCHARACTERIZED0.81positive
g22877.t1BTB/POZ DOMAIN-CONTAINING0.81positive
g30567.t1BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED0.80positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 54 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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