Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g33745.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g33745.t1
Gene ID Description PCC Relationship
g33745.t1ANKYRIN REPEAT PROTEIN1positive
g28523.t1FRIZZLED0.97positive
g8218.t1RNA POLYMERASE II-ASSOCIATED PROTEIN 10.96positive
g13202.t1CGI-41 METHYLTRANSFERASE0.96positive
g3626.t1FAS-ASSOCIATED PROTEIN0.95positive
g22005.t1ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 20.95positive
g28269.t1REGULATOR-RELATED0.95positive
g19052.t1NUCLEAR HORMONE RECEPTOR0.94positive
g29100.t1ZINC PHOSPHODIESTERASE ELAC PROTEIN 20.94positive
g5090.t1F18C1.6 PROTEIN0.94positive
g11620.t1--0.94positive
g20491.t1CARBON CATABOLITE REPRESSOR PROTEIN 40.94positive
g3591.t1SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA0.94positive
g28094.t1OXYGENASE-RELATED0.94positive
g22701.t1CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 20.94positive
g10103.t1--0.94positive
g6460.t1EARLY ENDOSOME ANTIGEN 10.93positive
g7071.t1FAM11A, B PROTEIN0.92positive
g7567.t1GEO07735P1-RELATED-RELATED0.92positive
g28249.t1BATTENIN0.92positive
g30788.t1LIM DOMAIN KINASE 10.92positive
g27715.t1POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 10.91positive
g8648.t1LIPOPOLYSACCHARIDE CHOLINEPHOSPHOTRANSFERASE LICD0.91positive
g14109.t1BTB/POZ DOMAIN-CONTAINING0.91positive
g3849.t1DC11 ACN9 HOMOLOG0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 84 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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