Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3404.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3404.t1
Gene ID Description PCC Relationship
g3404.t1CEREBRAL PROTEIN-11-RELATED1positive
g27187.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.98positive
g6430.t1SWAP-70 RECOMBINASE0.98positive
g8719.t1QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE0.97positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.97positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.97positive
g25542.t1RAB GTPASE-ACTIVATING PROTEIN 1-LIKE0.97positive
g29384.t1--0.97positive
g4160.t1--0.97positive
g10641.t1DYNEIN LIGHT INTERMEDIATE CHAIN0.97positive
g19246.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.97positive
g5326.t1D-GLUCURONYL C5-EPIMERASE0.96positive
g27755.t1HOMER0.96positive
g633.t1MOLTING PROTEIN MLT-40.96positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.96positive
g5818.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.96positive
g16763.t1--0.96positive
g20120.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.96positive
g35990.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 140.96positive
g27754.t1HOMER0.96positive
g4500.t1RIKEN CDNA 9930021J03 GENE0.96positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.96positive
g19336.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.96positive
g6210.t1METHYLMALONYL-COA MUTASE0.96positive
g6346.t1MERLIN/MOESIN/EZRIN/RADIXIN0.96positive
g12341.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.96positive
g11254.t1SPINSTER0.96positive
g2392.t1IP22168P0.96positive
g15081.t1-0.96positive
g9525.t1-0.96positive
g2757.t1--0.95positive
g1424.t1--0.95positive
g2179.t1NUCLEOPHOSMIN0.95positive
g13129.t1PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.95positive
g3586.t1NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 10.95positive
g8844.t1KINESIN-LIKE PROTEIN KIN-12D0.95positive
g13588.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR0.95positive
g6432.t1SWAP-70 RECOMBINASE0.95positive
g8962.t1ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.95positive
g572.t1ACTIN0.95positive
g23743.t1LD33804P0.95positive
g27362.t1ANDROGEN-INDUCED PROTEIN 1-RELATED0.95positive
g23297.t1PROTEIN DISPATCHED-RELATED0.94positive
g27302.t1GLYCERATE KINASE0.94positive
g13201.t1CYTOCHROME P450 FAMILY 40.94positive
g3620.t1CARBONIC ANHYDRASE0.94positive
g9737.t1--0.94positive
g33089.t1DNA2/NAM7 HELICASE FAMILY0.94positive
g7338.t1--0.94positive
g22154.t1N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D10.93positive
g2960.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 120.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 316 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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