Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3430.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3430.t1
Gene ID Description PCC Relationship
g3430.t1ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 151positive
g35246.t1CASEIN KINASE II SUBUNIT ALPHA0.94positive
g24959.t1--0.93positive
g2339.t1OBG GTPASE FAMILY0.93positive
g33033.t1DNA TOPOISOMERASE/GYRASE0.93positive
g14211.t1SMALL NUCLEAR RIBONUCLEOPROTEIN SM D20.92positive
g18374.t1PRE-MRNA-PROCESSING FACTOR 190.92positive
g11307.t1--0.91positive
g27193.t1RIBOSOMAL PROTEIN L190.91positive
g1868.t1UNCHARACTERIZED0.91positive
g18365.t1UNCHARACTERIZED0.91positive
g20828.t1CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED0.90positive
g15355.t1UBIQUITIN-ACTIVATING ENZYME E10.90positive
g8031.t1PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED0.90positive
g10086.t1TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN0.90positive
g21887.t1SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR0.90positive
g17462.t1TNF RECEPTOR ASSOCIATED FACTOR0.89positive
g9792.t1--0.88positive
g20659.t1DNA TOPOISOMERASE/GYRASE0.88positive
g10222.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 240.88positive
g18564.t1L1 TRANSPOSABLE ELEMENT-RELATED0.88positive
g31854.t1SMALL MEMBRANE PROTEIN-RELATED0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 85 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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