Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g34877.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g34877.t1
Gene ID Description PCC Relationship
g34877.t1LEUCOKININ RECEPTOR-RELATED1positive
g7906.t1POLYCYSTIN FAMILY MEMBER0.99positive
g6890.t1UNCHARACTERIZED0.99positive
g4058.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED0.99positive
g7884.t1--0.99positive
g3245.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g11666.t1TUMOR PROTEIN P53-INDUCIBLE PROTEIN 110.99positive
g26771.t1TOLL-LIKE RECEPTOR0.99positive
g10028.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN0.99positive
g4797.t1POLYCYSTIN-10.99positive
g5150.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g31403.t1--0.99positive
g30771.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g27015.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g2594.t1SYNAPTOTAGMIN0.99positive
g1848.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g3218.t1SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL0.99positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g10338.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.99positive
g8733.t1CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN0.99positive
g12573.t1VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT0.99positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.99positive
g7170.t1MONOCARBOXYLATE TRANSPORTER0.99positive
g27167.t1CENTROSOMAL PROTEIN 20.99positive
g498.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g5253.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g28694.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g17295.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED0.99positive
g26079.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.98positive
g7907.t1--0.98positive
g15144.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g12655.t1CATION TRANSPORTING ATPASE0.98positive
g23501.t1SLR5058 PROTEIN0.98positive
g6319.t1POLYCYSTIN-10.98positive
g26976.t1--0.98positive
g23090.t1RETROTRANSPOSON0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 191 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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