Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g35098.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g35098.t1
Gene ID Description PCC Relationship
g35098.t1TRANSIENT RECEPTOR POTENTIAL CHANNEL1positive
g22433.t1SLR5058 PROTEIN0.99positive
g7296.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g31641.t152 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED0.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g10338.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.99positive
g30478.t1--0.99positive
g23638.t1CXC2 DOMAIN-CONTAINING PROTEIN0.99positive
g14627.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g35485.t1MULTICOPPER OXIDASE-RELATED0.99positive
g4013.t1GUANYLYL CYCLASE0.99positive
g4220.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.99positive
g1085.t1-0.99positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.99positive
g8077.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g14393.t1COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING0.98positive
g6876.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.98positive
g14100.t1CENTROSOMAL PROTEIN 20.98positive
g2006.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g13443.t1SLR5058 PROTEIN0.98positive
g4096.t1MACOILIN0.98positive
g22110.t1DED DOMAIN-CONTAINING PROTEIN0.98positive
g1102.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g27767.t1DUAL SPECIFICITY PROTEIN KINASE0.98positive
g14969.t1RAN BINDING PROTEIN 9-RELATED0.98positive
g33838.t1POLYCYSTIN-10.98positive
g11499.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.98positive
g28829.t1RETROTRANSPOSON0.98positive
g13865.t1SUPERKILLER 3 PROTEIN-RELATED0.98positive
g33320.t1--0.98positive
g24900.t1--0.97positive
g5475.t1RAS-LIKE FAMILY MEMBER 110.97positive
g24071.t1SET DOMAIN-CONTAINING PROTEIN-RELATED0.97positive
g21934.t1HMG DOMAIN-CONTAINING PROTEIN 30.97positive
g29738.t1--0.96positive
g19250.t1--0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 145 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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