Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g35276.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g35276.t1
Gene ID Description PCC Relationship
g35276.t1--1positive
g28193.t1DNA HELICASE RECQ FAMILY MEMBER0.96positive
g5642.t1ARGININE/SERINE-RICH PROTEIN PNISR0.96positive
g8868.t1SI:CH211-161H7.5-RELATED0.96positive
g9270.t1DNA HELICASE RECQ FAMILY MEMBER0.95positive
g1859.t1--0.95positive
g8756.t1INSULIN GENE ENHANCER PROTEIN0.95positive
g28993.t1ENDONUCLEASE III-LIKE PROTEIN 10.95positive
g1192.t1UNCHARACTERIZED0.95positive
g3598.t1ETS0.95positive
g6668.t1--0.95positive
g1258.t1TESTIS DEVELOPMENT PROTEIN PRTD0.94positive
g20289.t1PROTEIN DD3-30.94positive
g12736.t1PROPERDIN0.94positive
g27013.t1RFX TRANSCRIPTION FACTOR FAMILY0.94positive
g16684.t1BATTENIN0.94positive
g5322.t1-0.94positive
g10156.t1CTP SYNTHASE0.94positive
g14204.t1MYELIN TRANSCRIPTION FACTOR 1-RELATED0.93positive
g11894.t1SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING0.93positive
g106.t1SYNAPTOTAGMIN0.93positive
g33211.t1--0.92positive
g23336.t1--0.92positive
g8563.t1--0.79positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 90 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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