Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g388.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g388.t1
Gene ID Description PCC Relationship
g388.t1ZINC FINGER PROTEIN-LIKE 11positive
g7613.t1CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-260.93positive
g19813.t1--0.92positive
g10479.t1GENETIC SUPPRESSOR ELEMENT 10.91positive
g35420.t1--0.91positive
g21488.t1SKP10.90positive
g20671.t1PRE-MRNA SPLICING FACTOR PRP80.90positive
g2558.t1--0.90positive
g18492.t1METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE0.89positive
g20125.t1CCCH ZINGC FINGER0.88positive
g785.t1SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 20.88positive
g833.t1RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN0.88positive
g7313.t1HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED0.88positive
g4472.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN0.87positive
g27722.t1--0.86positive
g8440.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 180.85positive
g6578.t1CLEAVAGE STIMULATION FACTOR SUBUNIT 20.85positive
g14794.t1PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL0.85positive
g11404.t1PHOSPHATIDYLINOSITOL TRANSFER PROTEIN0.85positive
g21369.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.84positive
g3167.t1LD11652P0.81positive
g6469.t1LYSINE-SPECIFIC DEMETHYLASE0.81positive
g2467.t1NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP10.77positive
g10133.t1PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP40.76positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 107 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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