Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3911.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3911.t1
Gene ID Description PCC Relationship
g3911.t1NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 11positive
g34952.t1LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN0.96positive
g8332.t1CD59 GLYCOPROTEIN0.96positive
g2712.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED0.96positive
g396.t1GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP10.96positive
g12697.t1COATOMER SUBUNIT EPSILON0.96positive
g32162.t1METHANETHIOL OXIDASE0.95positive
g31853.t1METALLOPROTEASE TLDD0.95positive
g27744.t1--0.95positive
g26069.t126S PROTEASOME REGULATORY SUBUNIT0.95positive
g30449.t1TRANSLATION FACTOR0.95positive
g7593.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.95positive
g13771.t1--0.95positive
g7181.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G0.95positive
g5588.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 80.95positive
g13779.t1MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM400.95positive
g27741.t1DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED0.94positive
g27963.t126S PROTEASOME REGULATORY SUBUNIT0.94positive
g9854.t1PROTEIN C6ORF1300.94positive
g15034.t126S PROTEASOME REGULATORY SUBUNIT0.94positive
g12385.t1OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 10.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 109 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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